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Since its groundbreaking FDA approval in 1997, quetiapine been a staple in mental health programs for more than 60 years. In 2008, The National Association of Clinical Mental Health Practitioners (NACPHPS) recognized Quetiapine as a “urga-like drug” that “offers a safe, effective, low-dose alternative to serotonin reuptake inhibitors (SSRIs)” (). The FDA approved quetiapine as the first “serotonin-norepinephrine reuptake inhibitor” (S-RI). Other versions of quetiapine exist, including Seroquel® (quetiapine), Seroquel® XR (quetiapine XR), Seroquel XR (quetiapine XR XR), Seroquel® SR (quetiapine SR), and Seroquel® SRX (quetiapine XR SR).
Quetiapine is used in adult patients to “treat bipolar disorder, to help patients stabilize mood, and to treat acute major depressive disorder (a depressive disorder) as early as possible.” ()
Quetiapine is also used in pediatric patients to “treat schizophrenia and bipolar disorder in children.” ()
Quetiapine is available in tablet form and as an oral tablet. The Food and Drug Administration (FDA) first approved Quetiapine in the 1950’s and “in 1998, Seroquel XR was approved for the treatment of major depressive disorder (MDD).” () Quetiapine was also first marketed as an extended-release tablet in 2009 ().
Seroquel® (quetiapine) is the brand name for the drug quetiapine, which comes in a 10 mg, 20 mg, and 40 mg tablet. Quetiapine XR, or quetiapine-based extended-release tablet, is available in a 56 mg, 64 mg, and 80 mg strength. The doses for Seroquel are between 60 and 120 mg per day, which can be increased to Seroquel 40 mg per day as an adjunct to mental health therapy. ()
Like all medications, Seroquel can cause side effects, although not everyone gets them. The most common side effects of Seroquel include:
Like all medications, Seroquel can interact with other medications, leading to potential side effects. The effects of Seroquel can include: ()
If you are hypersensitive to medications, you may experience these symptoms while you are using Seroquel. If you are pregnant, are nursing, or have any history of liver disease, your provider should discuss the risks and benefits of using Seroquel with you. Seroquel can also increase the risk of developing lactic acidosis ().
Seroquel should be stored at room temperature, away from moisture, heat, and light. Quetiapine should be kept in the original packaging to maintain its effectiveness.
Seroquel should not be transferred to other countries. Quetiapine can be conveniently used by those without expressuria in nursing homes, hospitals, and clinics.
Seroquel is not recommended for use in pregnant women unless explicitly stated otherwise in the medication’s packaging. It is not recommended for use in women who are pregnant or are planning to become pregnant. It is not recommended for use in pediatric patients or women 65 years or older unless explicitly stated otherwise.
Quetiapine, commonly sold under the brand name Seroquel, is a type of prescription medication called an antipsychotic drug. These medications often treat conditions that can cause psychosis or losing touch with reality, but they also help with different kinds of depression and anxiety—especially when first-line treatments aren’t enough.
There are two types of antipsychotic drugs. “Typical” antipsychotics refer to the first generation of these drugs, which were developed in the 1950s. “Atypical” antipsychotics, which were introduced in the 1990s, are considered second-generation drugs. They are just as effective as typical antipsychotics but are much less likely to cause complications such as movement and motor control problems.
Quetiapine is an atypical antipsychotic. It changes how certain chemicals (dopamine and serotonin) work in the brain.
Dopamine is a “chemical messenger” (neurotransmitter) that delivers instructions to nerve cells in the brain. It helps control mood, pleasure, motivation, memory, attention, and other functions. Serotonin is also a chemical messenger. It’s sometimes called the feel-good chemical because it helps regulate your mood and sense of well-being.
In people with depression or psychosis, dopamine and serotonin signals don’t work properly. Quetiapine works by blocking these abnormal signals.
QuetiapineOriginally a pharmacist, James E. McKillop, Jr. was the first to sell Seroquel, the first to treat schizophrenia. He soon became familiar with how the drug was made.
Inogie, R. V., and another pharmacist, Mark M. Blount, worked together, creating an antipsychotic that also helps treat bipolar disorder. They found that Seroquel also helped people with bipolar disorder by helping them focus, concentrate, and stay on task more quickly.
The U. S. Food and Drug Administration approved Quetiapine as an add-on therapy for the treatment of major depressive disorder (MDD). In 2002, the drug’s Clinical Development and Maximum Specialrictive Criteria (C. D. C.elleria) were created to enhance its effectiveness and safety. These criteria ensure that the drug remains effective in patients with moderate to severe MDD, has a good safety record, and is not associated with known serious side effects.
Quetiapine is available in the following doses:
Quetiapine is also available in a lower dose called a extended-release (long-acting) dose:
The effects of an antipsychotic can vary based on individual patient response, medical history, and response to the medication. The most common symptoms of an antipsychotic include:
If your symptoms are lightheaded or blurred, see a doctor immediately. An at-home symptom control measure may be recommended. Quetiapine is contraindicated in patients with a history of drug-induced autonomic instability.
Anergic states can happen in any time frame and in any patients (including those who have been taking quetiapine for long periods).
What is the difference between the two medications?
Medications like Seroquel and Quetiapine are the two most commonly prescribed medications for
Seroquel is a brand name for the drug
. However, there are many differences between the two medications
The first medication to be prescribed Seroquel is Quetiapine (quetiapine) – the generic version of the drug.
The second medication to be prescribed is Seroquel XR (extended release).
In this article, we will look at the main differences between the two medications.
Seroquel XR is a brand name for the drug
It is a combination medication used to treat major depressive disorder (MDD) in adults and children. It is a selective serotonin reuptake inhibitor (SSRI) that works by increasing the levels of a chemical called serotonin in the brain.
The main active ingredients in Seroquel XR are Quetiapine and Seroquel.
This medication is typically prescribed to treat adults with depression, and it is also used to treat adults with attention deficit disorder (ADHD) and bipolar disorder.
Both Seroquel XR and Seroquel XR XR are used to treat depression.
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